Search on: CHOLALIC ACIDS 
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Descriptor English:   Cholic Acids 
Descriptor Spanish:   ácidos cólicos 
Descriptor Portuguese:   Ácidos Cólicos 
Synonyms English:   Acids, Cholalic
Acids, Cholic
Cholalic Acids  
Tree Number:   D04.210.500.105.225
D04.210.500.221.430
Definition English:   The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics. 
Indexing Annotation English:   cholic acid glycine conjugate = GLYCOCHOLIC ACID; cholic acid taurine conjugate = TAUROCHOLIC ACID; CHOLIC ACID is also available
Pharmacological Action:   Gastrointestinal Agents
 
History Note English:   75; was CHOLIC ACID 1973-74 (Prov 1973), was CHOLIC ACID see under BILE ACIDS AND SALTS 1963-73 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   2843 
Unique Identifier:   D002793 

Occurrence in VHL: 		 

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